1
Xiaolin Wu, Joshua Raymond, Cheryl Chan, Yaoping Liu, Yie Hou Lee, Timothy Lu, Stacy Springs, Hanry Yu
"Accelerating cell therapy safety: rapid and accurate absolute quantification of adventitious agents using digital CRISPR approaches and beyond ", 15TH STEM CELL SOCIETY SINGAPORE SYMPOSIUM 2023; "STEM CELL INNOVATIONS IN RESEARCH AND HEALTHCARE", Nov 29, 2023-Dec 01, 2023, Singapore
2023
1
Wei-Xiang Sin, Narendra Suhas Jagannathan, Denise Bei Lin Teo, Faris Kairi, Dedy Sandikin, Ka-Wai Cheung, Yie Hou Lee, Rajeev J. Ram, Lisa Tucker-Kellogg, Michael E. Birnbaum
"High-density microbioreactor process designed for automated point-of-care manufacturing of CAR T cells", 15TH STEM CELL SOCIETY SINGAPORE SYMPOSIUM 2023; "STEM CELL INNOVATIONS IN RESEARCH AND HEALTHCARE", Nov 29, 2023-Dec 01, 2023, Singapore
2023
1
Shruthi Pandi Chelvam, Alice Ng Jie Ying, Huang Jiayi, Elizabeth Lee, Derrick Yong, Rajeev Ram, Stacy Springs, Rohan B.H. Williams
"Anomaly Detection for Microbial Contamination in Mesenchymal Stromal Cell Culture ", 15TH STEM CELL SOCIETY SINGAPORE SYMPOSIUM 2023; "STEM CELL INNOVATIONS IN RESEARCH AND HEALTHCARE", Nov 29, 2023-Dec 01, 2023, Singapore
2023
1
Xiaolin Wu, Joshua Raymond, Cheryl Chan, Yaoping Liu, Yie Hou Lee, Timothy Lu, Stacy Springs*, Hanry Yu*.
"Accelerating biomanufacturing safety: rapid and accurate absolute quantification of adventitious agents using digital CRISPR approaches", Recent Advances in Fermentation Technology (RAFT15), Oct 29, 2023-Nov 01, 2023, Naples, FL, USA.
2023
1
Xiaolin Wu, Joshua Jebaraj Raymond, Yaoping Liu, Alexander Jeremias Odermatt, Wei-Xiang Sin, Denise Teo, Inn Chuan Ng, Michael Birnbaum, Timothy Lu, Jongyoon Han, Stacy Springs* and Hanry Yu*.
"Multiplex Detection of Low Abundance Live Microorganisms Contamination in CAR-T cell manufacture using a Quantitative Digital Loop-mediated Isothermal Amplification Method", 2023 Annual Conference of the Biomedical Engineering Society (BMES2023), Oct 11, 2023-Oct 14, 2023, Seattle, WA, USA.
2023
1
Ching Ann Tee, Daniel Ninio Roxby, Antony Dhasan Josphin Denslin, Lisa Tucker-Kellogg, Laurie A. Boyer
"Metabolic modulation in MSC manufacturing to improve MSC therapeutic potential for articular cartilage repair. ", World Smart Bioprocessing Summit: Pharma 4.0 2023, , Sep 27, 2023-Sep 29, 2023, Berlin, Germany.
2023
1
Xiaolin Wu, Joshua Raymond, Cheryl Chan, Yaoping Liu, Yie Hou Lee, Timothy Lu, Stacy Springs, Hanry Yu
"Accelerating cell therapy safety: rapid and accurate absolute quantification of adventitious agents using digital CRISPR approaches and beyond", Singapore Cell & Gene Therapy Conference 2023, Aug 04, 2023-Aug 05, 2023, Singapore
2023
1
Joshua Raymond, Xiaolin Wu, Yaoping Liu, Alexander Jeremias Odermatt, Wei-Xiang Sin, Denise Teo, Michael Birnbaum, Timothy Lu , Jongyoon Han, Stacy Springs, Hanry Yu
"Multiplex Detection of Low Abundance Live Microorganisms Contamination in CAR-T cell manufacture using a Quantitative Digital Loop-mediated Isothermal Amplification Method", Singapore Cell & Gene Therapy Conference 2023, Aug 04, 2023-Aug 05, 2023, Singapore
2023
1
Ching Ann Tee, Daniel Ninio Roxby, Antony Dhasan Josphin Denslin, Lisa Tucker-Kellogg, Laurie A. Boyer
"Metabolic modulation in MSC manufacturing to improve MSC therapeutic potential for articular cartilage repair", Singapore Cell & Gene Therapy Conference 2023, Aug 04, 2023-Aug 05, 2023, Singapore
2023
1
Haoran Zhao, Xuanhe Zhao
"Mass-produce microcarrier for MSCs efficient expansion", Singapore Cell & Gene Therapy Conference 2023, Aug 04, 2023-Aug 05, 2023, Singapore
2023
1
Cheryl CHAN, Joanne LOH, Wei-Xiang SIN, Denise TEO, Michael BIRNBAUM, Rohan WILLIAMS, Stacy L. SPRINGS
"One-day Cell-free Viral RNA Test for Detecting Adventitious Viruses and Endogenous Viral Reactivation", Singapore Cell & Gene Therapy Conference 2023, Aug 04, 2023-Aug 05, 2023, Singapore
2023
1
Nicholas Ng Zhi Heng, Kerwin Kwek Zeming, Kai Yun Quek, Francesca Loraine Lim, Yunxin Chen, Chin Ren Goh, Faye Cheung Ka Wai, Sin Wei Xiang, Michael E. Birnbaum, Jongyoon Han
"Rapid Label-Free Profiling and CAR-T Biophysical Morphologies for Continuous Monitoring", Singapore Cell & Gene Therapy Conference 2023, Aug 04, 2023-Aug 05, 2023, Singapore
2023
1
Nicholas Tan Kwan Zen, Kerwin Kwek Zeming, Kai Yun Quek, Francesca Loraine Lim, Yunxin Chen, Chin Ren Goh, Nicholas Ng Zhi Heng, Michael E. Birnbaum, Jongyoon Han
"Rapid Assessment of immunological response in post-infusion CAR-T patients using biophysical WBC analysis", Singapore Cell & Gene Therapy Conference 2023, Aug 04, 2023-Aug 05, 2023, Singapore
2023
1
Linwei He, Jerome Tan, Shi Yan Ng, King Ho Holden Li, Jongyoon Han, Sing Yian Chew, and Han Wei Hou
"High Throughput Single Cell Impedance Bioanalysis of iPSC Neural Differentiation- for Rapid Safety and Efficacy Profiling", Singapore Cell & Gene Therapy Conference 2023, Aug 04, 2023-Aug 05, 2023, Singapore
2023
1
Jerome Tan, Jiahui Chen, Daniel Roxby, Wai Hon Chooi, Tan Dai Nguyen, Ng Shi Yan, Chew Sing Yian, Jongyoon Han
"Label-Free Assessment of Differentiation Efficiency in iPSC-derived Spinal Cord Progenitor Cells via Magnetic Resonance Relaxometry (MRR)", Singapore Cell & Gene Therapy Conference 2023, Aug 04, 2023-Aug 05, 2023, Singapore
2023
1
Kerwin Kwek Zeming, Kai Yun Quek, Wei-Xiang Sin, Ka-Wai Cheung, Michael E. Birnbaum, Jongyoon Han
"Rapid Label-free Microfluidic Assay for Profiling Functional Phenotypes of CAR T Cells: Towards Enhanced Manufacturing Control", Singapore Cell & Gene Therapy Conference 2023, Aug 04, 2023-Aug 05, 2023, Singapore
2023
1
Yaoping Liu, Sharon Yan Han Ling, Patrina Wei Lin Chua, Joshua Raymond, Xiaolin Wu, James Strutt, Peiying Ho, Megan Mcbee, Rohan Williams, Stacy L. Springs, Timothy K. Lu and Jongyoon Han
"Electrostatic microfiltration-based enrichment of low-abundance bacteria from large-volume samples improves the detection performances of digital PCR and sequencing", ECCMID 2023 the 33rd European Congress of Clinical Microbiology & Infectious Diseases), Apr 15, 2023-Apr 18, 2023, Copenhagen, Denmark
2023
1
Alice Ng, Jiayi Huang, Liang Cui, Joshua Raymond, Meenubharathi Natarajan, Yie Hou Lee, Stacy L. Springs
"Detection of microbial contaminations using nicotinic acid to nicotinamide ratio as a critical quality attribute to determine sterility in cell therapy products", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Cheryl Chan (SMART), Rohan Williams (NTU), Stacy L. Springs (MIT)
"Extracellular RNA Biomarkers for the Detection of Adventitious Virus Infection of Cells", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Ekta Makhija (SMART), Yang Zheng (NUS), Jiahao Wang (MBI), Han Ren Leong (NUS), Rashidah Binte Othman (SMART), Ee Xien Ng (SMART), Eng Hin Lee (NUS), Lisa Tucker-Kellogg (Duke-NUS), Yie Hou Lee (SMART), Hanry Yu (NUS), Zhiyong Poon (SGH), Krystyn J. Van Vliet (MIT
"Emergent patterns in mesenchymal stromal cell monolayer predict efficacy of cartilage formation", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Joshua Raymond (SMART), Xiaolin Wu (SMART), Yaoping Liu (SMART), Jongyoon Han (MIT), Timothy Lu (MIT), Hanry Yu (NUS)
"Rapid sterility testing of cell therapy products using a multiplex digital Loop-mediated isothermal amplification", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Kun Li (SMART), Arjav Shah (MIT), Patrick Doyle (MIT), Slaven Garaj (NUS)
"Nanopore tomography fingerprinting of viral particles in cell therapeutics", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
James P. B. Strutt (SMART), Meenubharathi Natarajan (SMART), Wei Xiang Sin (SMART), Elizabeth Lee (SMART), Paul W. Barone (MIT), Jacqueline M. Wolfrum (MIT), Rohan B. H. Williams (NTU), Scott A. Rice (NTU), Stacy L. Springs (MIT)
"Machine-learning based detection of adventitious agents in T cell therapy cultures using long read sequencing", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Nicholas Tan (SMART), Kerwin Kwek (SMART), Quek Kai Yun (SMART), Teo Kim Leng (A*STAR BTI), Loberas Mavis Gayle Lumawag (NUS), Steve Oh (A*STAR BTI), Hou Han Wei (NTU) Jongyoon Han (MIT)
"Mesenchymal stem cell enrichment augmented through microfluidics from bone marrow aspirate", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Wei-Xiang SIN (SMART), Denise TEO (SMART), Kevin S. LEE (Erbi Biosystems Inc), Harry LEE (Erbi Biosystems Inc), Narendra Suhas JAGANNATHAN (Duke-NUS), Rajeev RAM (MIT), Lisa TUCKER-KELLOGG (Duke-NUS), Michael BIRNBAUM (MIT)
"High Density CAR T Cell Culture with a 2-mL Continuous Perfusion Bioreactor", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Jerome Tan Zu Yao (NTU), Jiahui Chen (NTU), Daniel Roxby (NTU), Wai Hon Chooi (A*STAR IMCB), Tan Dai Nguyen (SMART), Ng Shi Yan (A*STAR IMCB), Sing Yian Chew (NTU), Jongyoon Han (MIT)
"Label-free assessment of differentiation efficiency in iPSC-derived Spinal Cord Progenitor Cells via Magnetic Resonance Relaxometry (MRR)", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Yanmeng Yang (SMART), Yingnan Wu (NUS), Jian Xiong Tan (NUS), Eng Hin Lee (NUS), Zheng Yang (NUS)
"Secretome derived from hypoxia preconditioned mesenchymal stem cells promote cartilage regeneration and mitigate joint inflammation via extracellular vesicles", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Zheng Yang (NUS), Dahou Yang (SMART), Yingnan Wu (NUS), Vinitha Denslin (NUS), Jaylen Tan (SMART), Eng Hin Lee (NUS), Jongyoon Han (MIT)
"Multi-dimensional double spiral microfluidic selection of MSC subpopulation with more efficacious chondrogenic potential", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Daniel Roxby (NTU), Tan Dai Nguyen (SMART), Jerome Tan (NTU), Jiahui Chen (NTU), Wai Hon Chooi (A*STAR IMCB), Shi-Yan Ng (A*STAR IMCB), Sing Yian Chew (NTU), Jongyoon Han (MIT)
"Magnetic Resonance Relaxometry as a Tool for Tracking Induced Pluripotent Stem Cell Variability", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Wei-Xiang SIN (SMART), Faye CHEUNG (SMART), Sandy LEE (A*STAR SIgN), Dedy SANDIKIN (SMART), Denise TEO (SMART), Faris KAIRI (SMART), Cheng-I WANG (A*STAR SIgN), Michael BIRNBAUM (MIT)
"Characterization of LVV-Transduced, In Vitro-Expanded Anti-TIM3 CAR T Cells", 14th Stem Cell Society Singapore Symposium 2022, Dec 07, 2022-Dec 09, 2022, Singapore
2022
1
Yaoping Liu (SMART), Joshua Raymond (SMART), Xiaolin Wu (SMART), Stacy L. Springs (MIT), Timothy K. Lu (MIT), Hanry Yu (NUS) and Jongyoon Han (MIT, SMART)
"Electrostatic Microfiltration Enriches Low-abundance Bacteria and Improves Downstream Detection", Micro Total Analysis Systems (MicroTAS 2022), Oct 23, 2022-Oct 27, 2022, Hangzhou, China
2022
1
Tan Dai Nguyen (SMART), Wai Hon Chooi (A*STAR IMCB), Jiahui Chen (NTU), Daniel Ninio Roxby (NTU), Jerome Tan Zu Yao (NTU), Hyungkook Jeon (MIT), Shi Yan Ng (A*STAR IMCB), Sing Yian Chew (NTU), Jongyoon Han (MIT)
"Label‐free and high‐throughput removal of residual undifferentiated iPSCs from their differentiated progenitor cells by inertial microfluidic cell sorter", Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference 2022, Oct 05, 2022-Oct 08, 2022, Jeju ICC, South Korea.
2022
1
Tan Dai Nguyen (SMART), Jiahui Chen (NTU), Quan Liu (Xiamen University), Lydia Chong (NTU), Sing Yian Chew (NTU), Jongyoon Han (MIT)
"Label‐free detection of residual undifferentiated iPSCs from their differentiated progenitor cells by microfluidic Raman spectroscopy", Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference 2022, Oct 05, 2022-Oct 08, 2022, Jeju ICC, South Korea.
2022
1
Jerome Tan Zu Yao, Jiahui Chen, Wai Hon Chooi, Daniel Roxby, Tan Dai Nguyen, Jongyoon Han, Sing Yian Chew
"Label‐free assessment of differentiation efficiency in induced pluripotent stem cell derived spinal cord progenitor cells via magnetic resonance relaxometry (MRR)", Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference 2022, Oct 05, 2022-Oct 08, 2022, Jeju ICC, South Korea.
2022
1
Zheng Yang, Ching Ann Tee, Yingnan Wu, Jongyoon Han, Eng Hin Lee
"A pre‐clinical animal study for zonal articular cartilage regeneration using stratified implantation of microcarrier expanded zonal chondrocytes", Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference 2022, Oct 05, 2022-Oct 08, 2022, Jeju ICC, South Korea.
2022
1
Daniel Roxby, Jiahui Chen, Jerome Tan Zu Yao, Tan Dai Nguyen, Sing Yian Chew, Jongyoon Han
"Magnetic resonance relaxometry as a tool for tracking induced pluripotent stem cell variability", Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference 2022, Oct 05, 2022-Oct 08, 2022, Jeju ICC, South Korea.
2022
1
Kevin S. Lee (Erbi Biosystems Inc.), Wei-Xiang Sin (SMART), Michael Birnbaum (MIT)
"Cell therapy process development with a 2 mL continuous perfusion bioreactor", 27th ESACT Meeting, Jun 26, 2022-Jun 29, 2022, Lisbon, Portugal
2022
1
Cheryl Chan (SMART), Rohan Williams (SCELSE), Stacy L. Springs (MIT)
"Detecting Adventitious Virus Infection of Cells Using Extracellular RNA Biomarkers", SDCT-REMEDIS Cell Therapy Conference, Jun 23, 2022-Jun 24, 2022, Virtual (Singapore)
2022
1
Wei-Xiang Sin (SMART), Kevin S. Lee (Erbi Biosystems Inc.), Harry Lee (Erbi Biosystems Inc.), Michael Birnbaum (MIT)
"High density CAR T cell culture with a 2 mL continuous perfusion bioreactor", SDCT-REMEDIS Cell Therapy Conference, Jun 23, 2022-Jun 24, 2022, Virtual (Singapore)
2022
1
Arjav Shah (MIT), Kun Li (SMART), Slaven Garaj (NUS), Patrick S. Doyle (MIT)
"Nanopore Tomography for Quantitative Assessment of fd bacteriophage diameter", Solid State to BioPhysics X, Jun 11, 2022-Jun 18, 2022, Dubrovnik, Croatia
2022
1
Kun Li (SMART), Arjav Shah*(MIT), Patrick S. Doyle (MIT), Slaven Garaj (NUS)
"Single-particle Methods on Quantitative Assessment of Geometrical Parameters of Small Viruses", Solid State to BioPhysics X, Jun 11, 2022-Jun 18, 2022, Dubrovnik, Croatia
2022
1
Wei-Xiang Sin
"Cell therapy process development with a 2 mL continuous perfusion bioreactor", A*STAR Advances in Cell and Gene Therapy (A*CGT) Symposium, May 11, 2022-Jun 12, 2022, Singapore
2022
1
Chelvam, S. P. (SMART), Lee, Elizabeth (SMART), Huang, J (SMART), Wu, Y. (A*STAR-BTI), Abdul Rahim (A*STAR-BTI), Rajeev Ram, R. (MIT), Yong, D. (A *STAR-SIMTech), & Springs, S. (MIT)
" Anomaly detection for microbial contamination in mesenchymal stromal cell culture", ISCT: Cytotherapy 2022, Process development and manufacturing, May 04, 2022-May 07, 2022, San Francisco, USA
2022
1
Zhi Xian Chan, Linxin Hou, Elizabeth Lee, Ching Ann Tee, and Derrick Yong
"Feature Analysis on Label-Free Multimodal Images of Mesenchymal Stromal Cells with Different Metabolic States", Microscopy Histopathology and Analytics 2022, Apr 24, 2022-Apr 27, 2022, Fort Lauderdale, Florida United States
2022
1
Kevin S. Lee (Erbi Biosystems Inc, Wei-Xiang Sin (SMART), Harry Lee (Erbi Biosystems Inc.), Michael Birnbaum (MIT)
"Erbi Biosystems - Cell culture development with a 2 mL continuous perfusion bioreactor", Advancing Manufacture of Cell and Gene Therapies VII, Engineering Conference International, Feb 06, 2022-Feb 10, 2022, Coronado, CA, USA
2022
1
N. Persits (MIT), C.C. Farruggio (MIT), Rajeev Ram (MIT), and K. Van Vliet (MIT)
"Metabolite Monitoring of Mesenchymal Stromal Cell Cultures by Spontaneous Raman Spectroscopy", Annual meeting of the American Institute of Chemical Engineers (AIChe), Nov 07, 2021-Nov 19, 2021, Virtual
2021
1
Elizabeth Lee (SMART), Maciej Baranski (SMART), Marvin Chew (SMART), Wei Xiang Sin (SMART), Ka-Wai Cheung (SMART), Lisa Tucker-Kellogg (Duke-NUS), Derrick Yong (A*STAR-SIMTech), Michael Birnbaum (MIT), and George Barbastathis (MIT)
"Supervised Dimensionality Reduction of Single-cell Features from Label-free Multimodal Images for T Cell Subtype Classification", Frontiers in Optics/Laser Science 2021, Nov 01, 2021-Nov 04, 2021, Virtual, Washington, DC United States
2021
1
Jiayi Huang (SMART), Thiara Sana Ahmed (NUS), Maciej Baranski (SMART), Elizabeth Lee (SMART), Shruthi Pandi Chelvam (SMART), Ying Ying Wu (A*STAR-BTI), Rajeev Ram (MIT), Scott Rice (NTU), Derrick Yong (A*STAR-SIMTech), and Stacy Springs (MIT)
"Machine Learning-Aided At-Line Detection of Bacterial marker NA for Cell Manufacturing", Frontiers in Optics/Laser Science 2021, Nov 01, 2021-Nov 04, 2021, Virtual, Washington, DC United States
2021
1
J. Kim (MIT), N. Persits (MIT), and R. J. Ram (MIT)
"Automated microfluidic Raman spectroscopy system", 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), Oct 10, 2021-Oct 14, 2021, Palm Springs, California, USA & Virtual
2021
1
Yong, Zixin (SMART), Elizabeth Lee (SMART), Maciej Baranski (SMART), Lisa Tucker-Kellogg (Duke-NUS), and George Barbastathis (MIT)
"CycleGAN for Reflection and Aberration Artifact Removal in Quantitative Phase Images of Mesenchymal Stromal Cells", Novel Techniques in Microscopy, Optical Society of America, April 2021., Apr 12, 2021-Apr 16, 2021, Virtual
2021
1
Kubal Sharvaj (NTU), Elizabeth Lee (SMART), Chor Yong Tay (NTU), and Derrick Yong (A*STAR-SIMTech)
"Multitrack Adaptive Compressive Hyperspectral Imaging for Cell Monitoring Applications", Frontiers in Optics 2020, Optical Society of America, Sep 14, 2020-Sep 17, 2020, Virtual, Washington, DC, United States
2020
1
Lee, Elizabeth (SMART), Maciej Baranski (SMART), Zixin Yong (SMART), Lakshmi Venkatraman (SMART), Derrick Yong (A*STAR-SIMTech), and George Barbastathis (MIT)
"Multimodal Microscopy for Label-free Monitoring of Mesenchymal Stromal Cells", Frontiers in Optics 2020, Optical Society of America, Sep 14, 2020-Sep 17, 2020, Virtual, Washington, DC, United States
2020
