Jongyoon Han

Professor of Biological Engineering and Electrical Engineering, MIT

HAN is a co-lead PI of SMART CAMP and co-captain of Flagship 1.

Website (External Link)

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Featured CAMP Publications

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Tan Dai Nguyen (SMART), Wai Hon Chooi (ASTAR-IMCB), Hyungkook Jeon MIT), Jiahui Chen (NTU), Jerome Tan (NTU), Daniel N. Roxby (SMART), Cheryl Yi-Pin Lee (ASTAR-IMCB), Shi-Yan Ng (ASTAR-IMCB), Sing Yian Chew (NTU), Jongyoon Han (SMART/MIT)

Label-Free and High-Throughput Removal of Residual Undifferentiated Cells From iPSC-Derived Spinal Cord Progenitor Cells

Stem Cells Translational Medicine, Advance access publication, ; Feb 07, 2024
2024

SMART CAMP Authors

1

Zheng Yang (NUS/SMART) , Yingnan Wu (NUS), Shu Hui Neo (SMART), Dahou Yang (SMART), Hyungkook Jeon (MIT), Ching Ann Tee (SMART), Vinitha Denslin (NUS), Daryl Jimian Lin (NUS) , Eng Hin Lee (NUS), Laurie A Boyer (MIT/SMART), Jongyoon Han (MIT/SMART)

Size-Based Microfluidic-Enriched Mesenchymal Stem Cell Subpopulations Enhance Articular Cartilage Repair

The American Journal of Sports Medicine, 52(2), pp 503-515; Feb 01, 2024
2024

SMART CAMP Authors

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Yang Z, Wu Y, Neo SH, Yang D, Jeon H, Tee CA, Denslin V, Lin DJ, Lee EH, Boyer LA, Han JY

Size-Based Microfluidic-Enriched Mesenchymal Stem Cell Subpopulations Enhance Articular Cartilage Repair

American Journal of Sports Medicine, published online; Jan 08, 2024
2024

SMART CAMP Authors

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Nicholas Tan Kwan Zen (SMART), Kerwin Kwek Zeming (SMART), Teo Kim Leng (A*STAR-BTI), Mavis Loberas (NUS), Jialing Lee (NUS), Goh Chin Ren (SMART), Yang Dahou (SMART), Steve Oh (A*STAR-BTI), James Hui Hoi Po (NUS), Simon M. Cool (A*STAR-IMCB), Han Wei Hou (NTU), Jongyoon Han (MIT/SMART)

Scalable Mesenchymal Stem Cells Enrichment from Bone Marrow Aspirate View Article Online using Deterministic Lateral Displacement (DLD) Microfluidics Sorting

Lab on a Chip (Published online); Sep 01, 2023
2023

SMART CAMP Authors

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Ching Ann Tee (SMART), Jongyoon Han (MIT/SMART), Hoi Po James Hui (NUS), Eng Hin Lee (NUS/SMART), and Zheng Yang (NUS/SMART)

Perspective in achieving stratified articular cartilage repair using zonal chondrocytes

Tissue Engineering Part B: Reviews., 29 (3), pp. 310-330; Jun 07, 2023
2023

SMART CAMP Authors

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Smitha Surendran Thamarath (SMART), Ching Ann Tee (SMART), Shu Hui Neo (SMART), Dahou Yang (SMART), Rashidah Othman (SMART), Laurie A Boyer (MIT/SMART), Jongyoon Han (MIT/SMART)

Rapid and Live-Cell Detection of Senescence in Mesenchymal Stem Cells by Micro Magnetic Resonance Relaxometry

Stem Cells Translational Medicine, 12 (5), pp. 266–280,; May 01, 2023
2023

SMART CAMP Authors

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Ching Ann Tee, Zheng Yang, Yingnan Wu, Xiafei Ren, Maciej Baranski, Daryl Jimian Lin, Afizah Hassan, Jongyoon Han, Eng Hin Lee

A Pre-Clinical Animal Study for Zonal Articular Cartilage Regeneration Using Stratified Implantation of Microcarrier Expanded Zonal Chondrocytes

Cartilage, April-June 2022, pp. 1-16; Apr 21, 2022
2022

SMART CAMP Authors

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Kerwin Kwek Zeming, Ri Lu, Kai Lee Woo, Guoyun Sun, Kai Yun Quek, Lih Feng Cheow, Chia-Hung Chen, Jongyoon Han, and Shir Lynn Lim

Multiplexed Single-Cell Leukocyte Enzymatic Secretion Profiling from Whole Blood Reveals Patient-Specific Immune Signature

Analytical Chemistry, 93 (10), pp. 4374–4382; Feb 18, 2021
2021

SMART CAMP Authors

1

Kerwin Kwek Zeming, Yuko Sato, Lu Yin, Nai-Jia Huang, Lan Hiong Wong, Hooi Linn Loo, Ying Bena Lim, Chwee Teck Lim, Jianzhu Chen, Peter R. Preiser, and Jongyoon Han

Microfluidic label-free bioprocessing of human reticulocytes from erythroid culture

Lab on a Chip, 20, pp. 3445-3460; Aug 14, 2020
2020

SMART CAMP Authors

1

Lu Yin, Zheng Yang, Yingnan Wu, Vinitha Denslin, Chia Chen Yu, Ching Ann Tee, Chwee Teck Lim, Jongyoon Han, Eng Hin Lee

Label-free separation of mesenchymal stem cell subpopulations with distinct differentiation potencies and paracrine effects

Biomaterials, 40, 119881; May 01, 2020
2020

SMART CAMP Authors

1

Taehong Kwon, Sung Hee Ko, Jean-François P. Hamel, and Jongyoon Han

Continuous Online Protein Quality Monitoring during Perfusion Culture Production Using an Integrated Micro/Nanofluidic System

Analytical Chemistry, 2020, 92 (7), pp. 5267-5275; Mar 13, 2020
2020

SMART CAMP Authors

Featured CAMP Presentations

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Yaoping Liu, Patrina Weilin Chua, Sharon Yan Han Ling, Joshua Raymond, James Strutt, Cheryl Siew Choo Chan, Peiying Ho, Megan Mcbee, Rohan Williams, Stacy L. Springs and Jongyoon Han

Electrostatic microfiltration-based enrichment of low-abundance bacteria from large-volume samples improves the detection performances of amplication-free Nanopore sequencing

microTAS 2023, , Katowice, Poland

SMART CAMP Authors

1

Yaoping Liu, Matilda Yu Yan Ong, Melody Xing Yen Song, Joshua Raymond, Chia-Ching Chan and Jongyoon Han

Electrostatic microfiltration performs better than the commercial kit in the isolation and detection of low-abundance cell-free DNA (cfDNA

microTAS 2023, , Katowice, Poland

SMART CAMP Authors

1

Tan Kwan Zen Nicholas, Kwek Zeming Kerwin, Quek Kaiyun, Goh Chin Ren, Ng Zhi Heng Nicholas, Michael E. Birnbaum, Yunxin Chen, Francesca Lorraine Lim Wei Inng, Jongyoon Han

Rapid assessment of immunological response in post-infusion CAR-T patients using biophysical WBC analysis

microTAS 2023, , Katowice, Poland

SMART CAMP Authors

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Xiaolin Wu, Joshua Jebaraj Raymond, Yaoping Liu, Alexander Jeremias Odermatt, Wei-Xiang Sin, Denise Teo, Inn Chuan Ng, Michael Birnbaum, Timothy Lu, Jongyoon Han, Stacy Springs* and Hanry Yu*.

Multiplex Detection of Low Abundance Live Microorganisms Contamination in CAR-T cell manufacture using a Quantitative Digital Loop-mediated Isothermal Amplification Method

2023 Annual Conference of the Biomedical Engineering Society (BMES2023), Seattle, WA, USA.

SMART CAMP Authors

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Joshua Raymond, Xiaolin Wu, Yaoping Liu, Alexander Jeremias Odermatt, Wei-Xiang Sin, Denise Teo, Michael Birnbaum, Timothy Lu , Jongyoon Han, Stacy Springs, Hanry Yu

Multiplex Detection of Low Abundance Live Microorganisms Contamination in CAR-T cell manufacture using a Quantitative Digital Loop-mediated Isothermal Amplification Method

Singapore Cell & Gene Therapy Conference 2023, Singapore

SMART CAMP Authors

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Nicholas Ng Zhi Heng, Kerwin Kwek Zeming, Kai Yun Quek, Francesca Loraine Lim, Yunxin Chen, Chin Ren Goh, Faye Cheung Ka Wai, Sin Wei Xiang, Michael E. Birnbaum, Jongyoon Han

Rapid Label-Free Profiling and CAR-T Biophysical Morphologies for Continuous Monitoring

Singapore Cell & Gene Therapy Conference 2023, Singapore

SMART CAMP Authors

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Nicholas Tan Kwan Zen, Kerwin Kwek Zeming, Kai Yun Quek, Francesca Loraine Lim, Yunxin Chen, Chin Ren Goh, Nicholas Ng Zhi Heng, Michael E. Birnbaum, Jongyoon Han

Rapid Assessment of immunological response in post-infusion CAR-T patients using biophysical WBC analysis

Singapore Cell & Gene Therapy Conference 2023, Singapore

SMART CAMP Authors

1

Linwei He, Jerome Tan, Shi Yan Ng, King Ho Holden Li, Jongyoon Han, Sing Yian Chew, and Han Wei Hou

High Throughput Single Cell Impedance Bioanalysis of iPSC Neural Differentiation- for Rapid Safety and Efficacy Profiling

Singapore Cell & Gene Therapy Conference 2023, Singapore

SMART CAMP Authors

1

Jerome Tan, Jiahui Chen, Daniel Roxby, Wai Hon Chooi, Tan Dai Nguyen, Ng Shi Yan, Chew Sing Yian, Jongyoon Han

Label-Free Assessment of Differentiation Efficiency in iPSC-derived Spinal Cord Progenitor Cells via Magnetic Resonance Relaxometry (MRR)

Singapore Cell & Gene Therapy Conference 2023, Singapore

SMART CAMP Authors

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Kerwin Kwek Zeming, Kai Yun Quek, Wei-Xiang Sin, Ka-Wai Cheung, Michael E. Birnbaum, Jongyoon Han

Rapid Label-free Microfluidic Assay for Profiling Functional Phenotypes of CAR T Cells: Towards Enhanced Manufacturing Control

Singapore Cell & Gene Therapy Conference 2023, Singapore

SMART CAMP Authors

1

Yaoping Liu, Sharon Yan Han Ling, Patrina Wei Lin Chua, Joshua Raymond, Xiaolin Wu, James Strutt, Peiying Ho, Megan Mcbee, Rohan Williams, Stacy L. Springs, Timothy K. Lu and Jongyoon Han

Electrostatic microfiltration-based enrichment of low-abundance bacteria from large-volume samples improves the detection performances of digital PCR and sequencing

ECCMID 2023 the 33rd European Congress of Clinical Microbiology & Infectious Diseases), Copenhagen, Denmark

SMART CAMP Authors

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Joshua Raymond (SMART), Xiaolin Wu (SMART), Yaoping Liu (SMART), Jongyoon Han (MIT), Timothy Lu (MIT), Hanry Yu (NUS)

Rapid sterility testing of cell therapy products using a multiplex digital Loop-mediated isothermal amplification

14th Stem Cell Society Singapore Symposium 2022, Singapore

SMART CAMP Authors

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Jerome Tan Zu Yao (NTU), Jiahui Chen (NTU), Daniel Roxby (NTU), Wai Hon Chooi (A*STAR IMCB), Tan Dai Nguyen (SMART), Ng Shi Yan (A*STAR IMCB), Sing Yian Chew (NTU), Jongyoon Han (MIT)

Label-free assessment of differentiation efficiency in iPSC-derived Spinal Cord Progenitor Cells via Magnetic Resonance Relaxometry (MRR)

14th Stem Cell Society Singapore Symposium 2022, Singapore

SMART CAMP Authors

1

Zheng Yang (NUS), Dahou Yang (SMART), Yingnan Wu (NUS), Vinitha Denslin (NUS), Jaylen Tan (SMART), Eng Hin Lee (NUS), Jongyoon Han (MIT)

Multi-dimensional double spiral microfluidic selection of MSC subpopulation with more efficacious chondrogenic potential

14th Stem Cell Society Singapore Symposium 2022, Singapore

SMART CAMP Authors

1

Daniel Roxby (NTU), Tan Dai Nguyen (SMART), Jerome Tan (NTU), Jiahui Chen (NTU), Wai Hon Chooi (A*STAR IMCB), Shi-Yan Ng (A*STAR IMCB), Sing Yian Chew (NTU), Jongyoon Han (MIT)

Magnetic Resonance Relaxometry as a Tool for Tracking Induced Pluripotent Stem Cell Variability

14th Stem Cell Society Singapore Symposium 2022, Singapore

SMART CAMP Authors

1

Yaoping Liu (SMART), Joshua Raymond (SMART), Xiaolin Wu (SMART), Stacy L. Springs (MIT), Timothy K. Lu (MIT), Hanry Yu (NUS) and Jongyoon Han (MIT, SMART)

Electrostatic Microfiltration Enriches Low-abundance Bacteria and Improves Downstream Detection

Micro Total Analysis Systems (MicroTAS 2022), Hangzhou, China

SMART CAMP Authors

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Tan Dai Nguyen (SMART), Wai Hon Chooi (A*STAR IMCB), Jiahui Chen (NTU), Daniel Ninio Roxby (NTU), Jerome Tan Zu Yao (NTU), Hyungkook Jeon (MIT), Shi Yan Ng (A*STAR IMCB), Sing Yian Chew (NTU), Jongyoon Han (MIT)

Label‐free and high‐throughput removal of residual undifferentiated iPSCs from their differentiated progenitor cells by inertial microfluidic cell sorter

Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference 2022, Jeju ICC, South Korea.

SMART CAMP Authors

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Tan Dai Nguyen (SMART), Jiahui Chen (NTU), Quan Liu (Xiamen University), Lydia Chong (NTU), Sing Yian Chew (NTU), Jongyoon Han (MIT)

Label‐free detection of residual undifferentiated iPSCs from their differentiated progenitor cells by microfluidic Raman spectroscopy

Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference 2022, Jeju ICC, South Korea.

SMART CAMP Authors

1

Jerome Tan Zu Yao, Jiahui Chen, Wai Hon Chooi, Daniel Roxby, Tan Dai Nguyen, Jongyoon Han, Sing Yian Chew

Label‐free assessment of differentiation efficiency in induced pluripotent stem cell derived spinal cord progenitor cells via magnetic resonance relaxometry (MRR)

Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference 2022, Jeju ICC, South Korea.

SMART CAMP Authors

1

Zheng Yang, Ching Ann Tee, Yingnan Wu, Jongyoon Han, Eng Hin Lee

A pre‐clinical animal study for zonal articular cartilage regeneration using stratified implantation of microcarrier expanded zonal chondrocytes

Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference 2022, Jeju ICC, South Korea.

SMART CAMP Authors

1

Daniel Roxby, Jiahui Chen, Jerome Tan Zu Yao, Tan Dai Nguyen, Sing Yian Chew, Jongyoon Han

Magnetic resonance relaxometry as a tool for tracking induced pluripotent stem cell variability

Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference 2022, Jeju ICC, South Korea.

SMART CAMP Authors