Alice obtained her bachelor's degree in Biomedical Science (with specialization in Cancer Biology) from University of Bradford, UK, and also obtained Master’s degree in Materials Science from Nanyang Technological University, Singapore. Her research interests are focused on the development of novel methods for the detection of microbial contaminations.

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She is currently working on the detection of microbial contaminations using nicotinic acid (NA) to nicotinamide (NAM) ratio as a critical quality attribute to determine sterility in cell therapy products. We have developed a novel rapid label-free non-invasive test for detecting and quantification of the microbial contamination in mammalian cell cultures. NA to NAM ratio was identified as a non-invasive critical quality attribute (CQA)for sterility. Importantly, only live microorganisms caused increases in this ratio. NA is uniquely present at high concentrations in bacteria-contaminated CTPs as compared to uncontaminated CTPs. This is due to he conversion from NAM by microbial nicotinamidases, which mammals lack. The NA to NAM ratio is a potential CQA for detection of microbial contaminations inCTPs and we are in the process of translating into a process analytical technology (PAT).

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In addition, a list of publications that I have worked on includes ‘AntimicrobialActivity and Cell Selectivity of Synthetic and Biosynthetic Cationic Polymers’,‘Multifunctional Polyphenols- and Catecholamines-Based Self-Defensive Films forHealth Care Applications’ and ‘Methods and strategies for the synthesis of diverse nanoparticles and their applications: a comprehensive overview’.

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