Critical Analytics for Manufacturing Personalized-Medicine, or SMART CAMP, is an Interdisciplinary Research Group in Singapore and at MIT focusing on better ways to produce living cells as medicine delivered to humans. CAMP launched in June 2019, with the goal to address two key bottlenecks facing production of a range of potential cell therapies: critical quality attributes (CQA) and process analytic technologies (PAT) for cell therapy production.
CAMP invents and demonstrate these CQA/PAT capabilities:
Our goal is that this applied research and the new workforce that develops with and for the manufacturing industry & clinics will provide more patients with access to promising, approved therapies.
The Singapore National Research Foundation supports this multi-million, multi-year project convening MIT and Singapore investigators and talented researchers from engineering, science, and clinical backgrounds.
CAMP works with academic labs, clinics, and companies to develop methods that identify, monitor, and manipulate the critical quality attributes of cells that correlate with positive therapeutic outcomes.
CAMP includes over 30 principal investigators (PIs) from Singapore-based universities and clinics and from MIT. CAMP is hiring highly motivated postdocs and research staff in Singapore and MIT, so check out our Team page for more info.
CAMP is the R&D core of a wider national effort on cell therapy manufacturing in Singapore.
MIT faculty in CAMP also conduct CAMP research at MIT, with several MIT PIs engaged in separate research efforts and collaborations in the USA.
Label-free critical quality attributes for personalized efficacy of cell therapies, including multivariate analysis of biological and biophysical attributes
Rapid critical quality attributes for safety of cell sources and cell therapy products, informing process analytic technologies and speeding product release
Process analytic technologies for cell proliferation and recovery, including inline and intermittent monitoring to promote efficacy and safety attributes for timely cell product release