SMART’s research in 2024: Pioneering Solutions to Address Societal Issues

In an era defined by rapid technological evolution and complex global challenges, the Singapore-MIT Alliance for Research and Technology (SMART) has continued to drive innovation that addresses some of the most pressing societal issues. From advancing sustainable technologies to revolutionising medical treatments, SMART combines MIT’s globally renowned applied innovation methodology with Singapore’s well-established R&D ecosystem to achieve market-ready breakthroughs.

Critical Analytics for Manufacturing Personalized-Medicine (CAMP): Medical Frontiers - A Leap in Personalised Treatments

SMART’s CAMP IRG focuses on innovations to improve the production of cellular therapies to increase patient access to approved and promising treatments by addressing key challenges in cell therapy manufacturing: critical quality attributes (CQA) and process analytic technologies (PAT), demonstrated on two prototypical cell therapy types - stem cells and T-cells for adoptive immunotherapies. Technologies and innovations include novel analytical tools that measure cellular attributes that correlate with therapeutic efficacy, rapid analytical tools that allow quick detection of bacteria, fungi or virus contamination during production, and processes that enable scalable manufacturing of often scarce cells for clinical use.

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