Faye Cheung

Research Scientist

Cheung Ka Wai, Faye obtained my PhD from The University of Hong Kong in 2010. Afterwards, he has been a postdoctoral fellow at the AIDS Institute, The University of Hong Kong and at Emerging Infectious Diseases Programme, Duke-NUS Medical School inSingapore. He has been fascinated in T cell immunology since his PhD. During and has gained experience in various aspects of T cell research, with major focus on drug development for modulating T cell responses and the role of T cells in infectious diseases, e.g. HIV-1/AIDS and Dengue. He has published in the Journal of Infectious Diseases, Journal of Virology, PLOSOne, Journal of Ethnopharmacology, etc.. Besides, he was the Principal investigator and co-investigator for some funded research projects.

In SMART-CAMP, he is working in Associate Prof. Michael Birnbaum’s team to identify the label-free critical quality attributes (CQAs) for monitoring the chimeric antigen receptor-T cells (CAR-T) manufacturing process. My current research is mainly focusing on investigating the use of soluble factors in the cell culture, e.g. metabolites for evaluating the healthiness of T cell proliferation. Asan immunologist in SMART-CAMP, I also work with colleagues from engineering background to investigate the potential application of technologies e.g. Deterministic LateralDisplacement (DLD) microfluidic technology and Magnetic Resonance Relaxometry (MMR) for improving CAR-T manufacture process.

Website (External Link)

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Featured CAMP Publications

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Ri Lu (NUS), Yan Shan Ang (NUS), Ka-Wai Cheung (SMART), Kai Yun Quek (SMART), Wei-Xiang Sin (SMART), Elizabeth Lee (SMART), Shir Lynn Lim (NUS), Lin-Yue Lanry Yung (NUS), Michael E. Birnbaum (MIT/SMART), Jongyoon Han (MIT/SMART), Lih Feng Cheow (NUS), Kerwin Kwek Zeming (SMART)

iSECRETE: Integrating Microfluidics and DNA Proximity Amplification for Synchronous Single-Cell Activation and IFN-𝜸 Secretion Profiling

Adv. Sci. 2024, 2309920; Aug 22, 2024
2024

SMART CAMP Authors

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Wei-Xiang Sin (SMART), N. Suhas Jagannathan (SMART), Denise Bei Lin Teo (SMART), Faris Kairi (SMART), Shin Yie Fong (ASTAR-IMCB), Joel Heng Loong Tan (ASTAR-IMCB), Dedy Sandikin (SMART), Ka-Wai Cheung (SMART), Yen Hoon Luah (SMART), Xiaolin Wu (SMART), Joshua Jebaraj Raymond (SMART), Francesca Lorraine Wei Inng Lim (ACTRIS/SGH), Yie Hou Lee (SMART), Michaela Su-Fern Seng (SingHealth), Shui Yen Soh (SingHealth), Qingfeng Chen (ASTAR-IMCB), Rajeev J. Ram (SMART/MIT), Lisa Tucker-Kellogg (Duke-NUS) & Michael E. Birnbaum (SMART/MIT)

A high-density microfluidic bioreactor for the automated manufacturing of CAR T cells

Nature Biomedical Engineering, Published online; Jun 04, 2024
2024

SMART CAMP Authors

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James P. B. Strutt (SMART), Meenubharathi Natarajan (SMART), Elizabeth Lee (SMART), Denise Bei Lin Teo (SMART), Wei-Xiang Sin (SMART), Faye Ka-Wai Cheung (SMART), Marvin Chew (SMART), Khaing Thazin (SMART), Paul W. Barone (MIT), Jacqueline M. Wolfrum (MIT), Rohan B. H. Williams (NUS), Scott A. Rice (NTU), Stacy L. Springs (MIT),

Machine-learning based detection of adventitious microbes in T-cell therapy cultures using long read sequencing

ASM Microbiology Spectrum (Published online); Aug 30, 2023
2023

SMART CAMP Authors

Featured CAMP Presentations

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Sin, WX. (SMART), Jagannathan, N.S.(SMART, Duke-NUS), Teo, D.B.L. (SMART), Kairi F. (SMART), Fong S.Y. (IMCB, A*STAR), Tan J.H.L.** (IMCB, A*STAR), Sandikin D. (SMART), Cheung K.W.** (SMART), Luah Y.H.** (SMART), Wu X.** (SMART), Raymond J.J. (SMART), Lim F.L.W.I. (SGH, SingHealth), Lee Y.H. (SMART), Seng M.S.F. (KKH, SingHealth), Soh S.Y. (KKH, SingHealth), Chen Q. (IMCB, A*STAR), Ram R.J. (MIT), Tucker-Kellogg L. (Duke-NUS), Birnbaum M.E. (MIT)

A high-density microfluidic bioreactor for the automated manufacturing of CAR T cells

Singapore Cell and Gene Therapy Pan Asia Summit 2024, Singapore

SMART CAMP Authors

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Wei-Xiang Sin, Narendra Suhas Jagannathan, Denise Bei Lin Teo, Faris Kairi, Dedy Sandikin, Ka-Wai Cheung, Yie Hou Lee, Rajeev J. Ram, Lisa Tucker-Kellogg, Michael E. Birnbaum

High-density microbioreactor process designed for automated point-of-care manufacturing of CAR T cells

15TH STEM CELL SOCIETY SINGAPORE SYMPOSIUM 2023; "STEM CELL INNOVATIONS IN RESEARCH AND HEALTHCARE", Singapore

SMART CAMP Authors

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Nicholas Ng Zhi Heng, Kerwin Kwek Zeming, Kai Yun Quek, Francesca Loraine Lim, Yunxin Chen, Chin Ren Goh, Faye Cheung Ka Wai, Sin Wei Xiang, Michael E. Birnbaum, Jongyoon Han

Rapid Label-Free Profiling and CAR-T Biophysical Morphologies for Continuous Monitoring

Singapore Cell & Gene Therapy Conference 2023, Singapore

SMART CAMP Authors

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Kerwin Kwek Zeming, Kai Yun Quek, Wei-Xiang Sin, Ka-Wai Cheung, Michael E. Birnbaum, Jongyoon Han

Rapid Label-free Microfluidic Assay for Profiling Functional Phenotypes of CAR T Cells: Towards Enhanced Manufacturing Control

Singapore Cell & Gene Therapy Conference 2023, Singapore

SMART CAMP Authors

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Wei-Xiang SIN (SMART), Faye CHEUNG (SMART), Sandy LEE (A*STAR SIgN), Dedy SANDIKIN (SMART), Denise TEO (SMART), Faris KAIRI (SMART), Cheng-I WANG (A*STAR SIgN), Michael BIRNBAUM (MIT)

Characterization of LVV-Transduced, In Vitro-Expanded Anti-TIM3 CAR T Cells

14th Stem Cell Society Singapore Symposium 2022, Singapore

SMART CAMP Authors

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Elizabeth Lee (SMART), Maciej Baranski (SMART), Marvin Chew (SMART), Wei Xiang Sin (SMART), Ka-Wai Cheung (SMART), Lisa Tucker-Kellogg (Duke-NUS), Derrick Yong (A*STAR-SIMTech), Michael Birnbaum (MIT), and George Barbastathis (MIT)

Supervised Dimensionality Reduction of Single-cell Features from Label-free Multimodal Images for T Cell Subtype Classification

Frontiers in Optics/Laser Science 2021, Virtual, Washington, DC United States

SMART CAMP Authors