Copyright ©2023 SMART CAMP
Wei-Xiang SIN is currently a Research Scientist in SMART-CAMP program. He is focussing on the investigation of critical quality attributes (CQAs) and critical process parameters (CPPs), and in helping with the development of process analytical technologies (PATs), related to the efficacy and safety of cell and gene therapy manufacturing, by leveraging a novel cell culture-on-a-chip platform technology, as well as by collaborating with other researchers at SMART CAMP. He is a molecular immunologist by training, having graduated from the inaugural Singapore Immunology Network (SIgN)-Nanyang Technological University(NTU) Joint Immunology PhD Program at the Agency for Science, Technology andResearch (A*STAR). Prior to joining SMART CAMP, he pursued postdoctoral training with the Synthetic Biology group at the Genome Institute of Singapore (GIS, A*STAR) and with the Translational Immunology group at the Institute of Molecular and Cell Biology (IMCB, A*STAR), as well as gained industry startup experience at a Good Manufacturing Practice (GMP)-certified Contract Development and ManufacturingOrganization (CDMO) that specializes in the production of clinical-grade lenti viral vectors for translational and commercial cell and gene therapies.
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His current projects include,
(a) High-throughput process characterization and development, and efficient scale-out of CAR T cell manufacturing on a microbioreactor.
(b) CAR-or donor-specific versus CAR- or donor-agnostic biological, biophysical, biochemical and/or metabolic attributes of CAR T cell effectiveness and persistence.
(c) Production and characterization of lentiviral vector-transduced anti-TIM3 CAR T cells for AML immunotherapy (in collaboration with IMPACT, A*STAR).
Website (External Link)
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Ri Lu (NUS), Yan Shan Ang (NUS), Ka-Wai Cheung (SMART), Kai Yun Quek (SMART), Wei-Xiang Sin (SMART), Elizabeth Lee (SMART), Shir Lynn Lim (NUS), Lin-Yue Lanry Yung (NUS), Michael E. Birnbaum (MIT/SMART), Jongyoon Han (MIT/SMART), Lih Feng Cheow (NUS), Kerwin Kwek Zeming (SMART)
SMARTÂ CAMPÂ Authors
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Wei-Xiang Sin (SMART), N. Suhas Jagannathan (SMART), Denise Bei Lin Teo (SMART), Faris Kairi (SMART), Shin Yie Fong (ASTAR-IMCB), Joel Heng Loong Tan (ASTAR-IMCB), Dedy Sandikin (SMART), Ka-Wai Cheung (SMART), Yen Hoon Luah (SMART), Xiaolin Wu (SMART), Joshua Jebaraj Raymond (SMART), Francesca Lorraine Wei Inng Lim (ACTRIS/SGH), Yie Hou Lee (SMART), Michaela Su-Fern Seng (SingHealth), Shui Yen Soh (SingHealth), Qingfeng Chen (ASTAR-IMCB), Rajeev J. Ram (SMART/MIT), Lisa Tucker-Kellogg (Duke-NUS) & Michael E. Birnbaum (SMART/MIT)
SMARTÂ CAMPÂ Authors
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James P. B. Strutt (SMART), Meenubharathi Natarajan (SMART), Elizabeth Lee (SMART), Denise Bei Lin Teo (SMART), Wei-Xiang Sin (SMART), Faye Ka-Wai Cheung (SMART), Marvin Chew (SMART), Khaing Thazin (SMART), Paul W. Barone (MIT), Jacqueline M. Wolfrum (MIT), Rohan B. H. Williams (NUS), Scott A. Rice (NTU), Stacy L. Springs (MIT),
SMARTÂ CAMPÂ Authors
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Wu T (NUS), Tan JHL (A*STAR-IMCB), Sin WX (SMART), Luah YH (SMART), Tan SY (A*STAR-IMCB), Goh M (A*STAR-IMCB), Birnbaum ME (MIT), Chen Q (A*STAR-IMCB), Cheow LF (NUS)
SMARTÂ CAMPÂ Authors
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Sin, WX. (SMART), Jagannathan, N.S.(SMART, Duke-NUS), Teo, D.B.L. (SMART), Kairi F. (SMART), Fong S.Y. (IMCB, A*STAR), Tan J.H.L.** (IMCB, A*STAR), Sandikin D. (SMART), Cheung K.W.** (SMART), Luah Y.H.** (SMART), Wu X.** (SMART), Raymond J.J. (SMART), Lim F.L.W.I. (SGH, SingHealth), Lee Y.H. (SMART), Seng M.S.F. (KKH, SingHealth), Soh S.Y. (KKH, SingHealth), Chen Q. (IMCB, A*STAR), Ram R.J. (MIT), Tucker-Kellogg L. (Duke-NUS), Birnbaum M.E. (MIT)
SMARTÂ CAMPÂ Authors
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Sin Wei-Xiang
SMARTÂ CAMPÂ Authors
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Wei-Xiang Sin, Narendra Suhas Jagannathan, Denise Bei Lin Teo, Faris Kairi, Dedy Sandikin, Ka-Wai Cheung, Yie Hou Lee, Rajeev J. Ram, Lisa Tucker-Kellogg, Michael E. Birnbaum
SMARTÂ CAMPÂ Authors
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Xiaolin Wu, Joshua Jebaraj Raymond, Yaoping Liu, Alexander Jeremias Odermatt, Wei-Xiang Sin, Denise Teo, Inn Chuan Ng, Michael Birnbaum, Timothy Lu, Jongyoon Han, Stacy Springs* and Hanry Yu*.
SMARTÂ CAMPÂ Authors
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Joshua Raymond, Xiaolin Wu, Yaoping Liu, Alexander Jeremias Odermatt, Wei-Xiang Sin, Denise Teo, Michael Birnbaum, Timothy Lu , Jongyoon Han, Stacy Springs, Hanry Yu
SMARTÂ CAMPÂ Authors
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Cheryl CHAN, Joanne LOH, Wei-Xiang SIN, Denise TEO, Michael BIRNBAUM, Rohan WILLIAMS, Stacy L. SPRINGS
SMARTÂ CAMPÂ Authors
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Nicholas Ng Zhi Heng, Kerwin Kwek Zeming, Kai Yun Quek, Francesca Loraine Lim, Yunxin Chen, Chin Ren Goh, Faye Cheung Ka Wai, Sin Wei Xiang, Michael E. Birnbaum, Jongyoon Han
SMARTÂ CAMPÂ Authors
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Kerwin Kwek Zeming, Kai Yun Quek, Wei-Xiang Sin, Ka-Wai Cheung, Michael E. Birnbaum, Jongyoon Han
SMARTÂ CAMPÂ Authors
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James P. B. Strutt (SMART), Meenubharathi Natarajan (SMART), Wei Xiang Sin (SMART), Elizabeth Lee (SMART), Paul W. Barone (MIT), Jacqueline M. Wolfrum (MIT), Rohan B. H. Williams (NTU), Scott A. Rice (NTU), Stacy L. Springs (MIT)
SMARTÂ CAMPÂ Authors
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Nicholas Tan (SMART), Kerwin Kwek (SMART), Quek Kai Yun (SMART), Teo Kim Leng (A*STAR BTI), Loberas Mavis Gayle Lumawag (NUS), Steve Oh (A*STAR BTI), Hou Han Wei (NTU) Jongyoon Han (MIT)
SMARTÂ CAMPÂ Authors
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Wei-Xiang SIN (SMART), Denise TEO (SMART), Kevin S. LEE (Erbi Biosystems Inc), Harry LEE (Erbi Biosystems Inc), Narendra Suhas JAGANNATHAN (Duke-NUS), Rajeev RAM (MIT), Lisa TUCKER-KELLOGG (Duke-NUS), Michael BIRNBAUM (MIT)
SMARTÂ CAMPÂ Authors
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Wei-Xiang SIN (SMART), Faye CHEUNG (SMART), Sandy LEE (A*STAR SIgN), Dedy SANDIKIN (SMART), Denise TEO (SMART), Faris KAIRI (SMART), Cheng-I WANG (A*STAR SIgN), Michael BIRNBAUM (MIT)
SMARTÂ CAMPÂ Authors
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Kevin S. Lee (Erbi Biosystems Inc.), Wei-Xiang Sin (SMART), Michael Birnbaum (MIT)
SMARTÂ CAMPÂ Authors
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Wei-Xiang Sin (SMART), Kevin S. Lee (Erbi Biosystems Inc.), Harry Lee (Erbi Biosystems Inc.), Michael Birnbaum (MIT)
SMARTÂ CAMPÂ Authors
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Wei-Xiang Sin
SMARTÂ CAMPÂ Authors
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Kevin S. Lee (Erbi Biosystems Inc, Wei-Xiang Sin (SMART), Harry Lee (Erbi Biosystems Inc.), Michael Birnbaum (MIT)
SMARTÂ CAMPÂ Authors
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Elizabeth Lee (SMART), Maciej Baranski (SMART), Marvin Chew (SMART), Wei Xiang Sin (SMART), Ka-Wai Cheung (SMART), Lisa Tucker-Kellogg (Duke-NUS), Derrick Yong (A*STAR-SIMTech), Michael Birnbaum (MIT), and George Barbastathis (MIT)
SMARTÂ CAMPÂ Authors